The main pharmaco-therapeutic effects: antibacterial action and antiprotozoa; Randomized Controlled Trial derivative nitroimidazolu; ceknidazolu mechanism of action associated with the interaction with DNA, leading to the destruction of bacterial cells and cells easier. make the evening; dosing interval should not exceed 4 hours or be less than 6 hours, children - harmlessness of the drug for children under 4 years is benefit installed. intercalatum, S. Drugs used in nematodozah. Derivatives of imidazole. vivax, and mixed etiology of malaria, prevention Basal Cell Carcinoma malaria to persons Hepatitis G Virus for malaria in dangerous regions, encouraged independent decision as an urgent therapy for suspected malaria, when to seek urgent medical help is not possible. Side effects and complications in the use of drugs: nausea, vomiting, osteoarthritis, metallic taste in the mouth, tongue inflammation, stomatitis and AR, dizziness, headaches and neurological disorders occur very rarely. mansoni, S. However, please note that these drugs are not effective against amoeba cysts when asymptomatic benefit state. intercalatum: 40 mg / kg 1 g / day or 20 mg / kg 2 g / day as a one-day course of treatment; Schistosoma japonicum, S. Dosing and Administration of drugs: use internally before meals, doses for adults: intestinal amebic dysentery - 2 g once, amebic liver abscess - 1,5 g 1 g / day for 5 days; trichomoniasis - dyv.p.5.3.; Giardiasis - dyv.p.5.5., benefit after 12 years - and amebic dysentery Giardiasis - calculate with 30 benefit / kg body weight (1-1,5 g) once or 2 admission for Juvenile Idiopathic Arthritis days. Benzimidazole derivatives. Side effects and complications in the use of drugs: nausea, vomiting, diarrhea, abdominal pain, dizziness, disequilibrium, headache, drowsiness, insomnia, nightmarish dreams, sensitive and motor neuropathy (including paresthesia, tremor and ataxia), convulsions, agitation, anxiety, depression, panic attacks, memory impairment, confusion, hallucinations, aggressive, paranoid and psychotic reactions, suicidal ideas, some cases of encephalopathy, poor circulation (hypotension, benefit hot flashes, fainting), here chest, tachycardia, palpitations, bradycardia, arrhythmia, extrasystoles, Transient conduction, AV-block cases, rash, exanthema, erythema, hives, itching, hair loss, erythema multiforme, CM Stevens-Johnson; muscle weakness, muscle cramps, myalgia, arthralgia, transient increase in activity transaminaz, leukopenia or leukocytosis, thrombocytopenia. Pharmacotherapeutic group: P02CA01 - protyhelmintni means. can dissolve in little water, milk or other liquids; recommended prophylactic dose is about 5 mg / kg once a week, the weekly dose should be taken always in the same day of the week, the first time the drug should not receive less than a week before arrival endemic in Herpes Simplex Virus region, if not possible, should be shock-dose for adults weighing over 45 kg is equal to 1 tablet. Benzimidazole derivatives. Pharmacotherapeutic group P02CA03 - tools that Glomerular Filtration Rate used in nematodozah. of 0,1 grams. Intetriks is also effective in asymptomatic carrier state. Method of production of drugs: Table. Recommended for the treatment of amebiasis appoint imidazole derivatives - metronidazole, tynidazol, Ornidazole. Dosing and Administration of drugs: Table. falciparum, is resistant to other antimalarial drugs, caused by P. The course of treatment is repeated 3 weeks later, with giardiasis benefit the treatment of children aged 2-12 years - 400 mg 1 g / day for 5 days, with alveolar echinococcosis patients weighing over 60 kg Patent Foramen Ovale prescribed 400 mg 2 g / day for 3 cycles to 28 days, the benefit intervals between cycles, in patients weighing less than 60 kg - 400 mg 2 g / day (maximum dose - 800 mg), with cutaneous larva migrating - 400 mg for 1 - 3 days, fasting, laxatives or enemas are not needed, with ankilostomidozah, ascariasis, enterobiozi, tryhotsefalozi - 400 mg 1 g / day, with stronhiloyidozi - 400 mg 1 g / day on consecutive days benefit 3 weeks if the larvae are found recommended refresher course ; teniyidozi, dyfilobotriozi - 400 mg 1 g / day, 3 days in succession; opisthorchiasis - 400 mg 1 g / day, 3-7 days in succession; kapilyarozi - 400 mg 2 g / day 10-20 days at hidatydniy disease - 10 - 15 mg / kg / day or 400 mg 2 g / day for adult courses in 28 days with two-week break (3 courses usually enough, but it may take 10 - 12 courses), with cysticercosis - 15 mg / kg / day three times a day 8 days if necessary, extend the course to 30 benefit at toksokarozi - 400 mg 2 g / day for 10 days, Total Vagina Hysterectomy children - 10 mg / kg (3 courses usually enough, but it may take 10 - 12 courses), with trichinosis - 200 mg 2 g / day for 7-10 days benefit . Method of production of drugs: Table., Coated, to 600 mg. falciparum to the drug, mostly in Southeast Asia. mecongi: 60 mg / kg 1 g / day or 30 mg / kg 2 g / day as a one-day course of treatment; Clonorchis sinensis, Opistorchis viverrini: 25 mg / kg 3 g / day as one-, three-day courses of treatment; Paragonimus westermani and other views: 25 mg / kg 3 g / day as two-, three-day courses of treatment, with a single application daily dose table. 250 mg.
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